Overeating increases brain’s insulin resistance

A new study conducted by Christoph Buettner, M.D., Ph.D., of the Mount Sinai School of Medicine indicates that overeating may be tied to insulin resistance in the brain.

Buettner’s previous research, which was published in The Journal of Biological Chemistry, showed that brain insulin is key in controlling lipolysis, which is when triglycerides from fat are broken down and byproducts are released. When lipolysis is not controlled due to insulin resistance, fatty acid levels rise. This can lead to the development of type 2 diabetes.

Buettner’s newest research aimed to find out what causes insulin resistance in the brain. He and his group of researchers fed a group of rats a diet rich in fat for three days, which caused a 50 percent increase in their calorie levels. They then put a tiny amount of insulin in the brains of the rats, which had previously been effective at curbing the release of fatty acids and glucose in the animals. The results showed that after their three days of high calorie intake, the rats developed insulin resistance. The researchers believe that overeating has the same effect in humans.

“When you overeat, your brain becomes unresponsive to these important clues such as insulin, which puts you on the road to diabetes,” said Dr. Buettner. “We believe that what happens in rats also happens in humans.”

Diabetes prevention
The Mayo Clinic notes that exercise is effective in warding off diabetes. It helps people lose weight, lowers blood sugar and increases sensitivity to insulin. The source also reports that a diet that’s high in fiber is also useful for preventing diabetes, because it can help control blood sugar and allow people to eat less due to fiber’s filling effect.

According to the the University of Maryland, consuming omega-3 fatty acids can help people with diabetes because it can lower triglycerides and apoproteins, which are indicators of the ailment. Omega-3s are found in chia seeds, help milk and you can also get them in an Omegakrill supplement from Dr. Newton’s Naturals.

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